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Thursday, May 5, 2016
Federal government bans e-cig sales to minors
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fvideos%2Ffederal-government-bans-e-cig-sales-to-minors%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Is Meat Killing Us? Mayo Clinic Doctor Discusses Findings
From: Mayo Clinic http://redirect.viglink.com?u=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DbO08mOX7xAY&key=ddaed8f51db7bb1330a6f6de768a69b8
Steps to reduce a common health threat to seniors
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Fcdc-minimize-seniors-risk-of-falling%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Your Healthy Skin Germs Stay Put, Despite Cleaning
Findings suggest your 'microbial fingerprint' is important to well-being
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fskin-problems-and-treatments%2Fnews%2F20160505%2Fyour-healthy-skin-germs-stay-put-despite-cleaning%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Rodeo Champion Shares Story of Hope After Brain Tumor Treatment
From: Mayo Clinic http://redirect.viglink.com?u=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DupHis1uFI3c&key=ddaed8f51db7bb1330a6f6de768a69b8
Dr. Haraldur Bjarnason- Vascular Interventional Radiologist, Mayo Clinic
From: Mayo Clinic http://redirect.viglink.com?u=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DbFLlWOLWeNA&key=ddaed8f51db7bb1330a6f6de768a69b8
Widely Used Heart Drug Tied to Dementia Risk
Both warfarin and the atrial fibrillation it's often used to treat may raise risk, study suggests
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fheart-disease%2Fnews%2F20160505%2Fwidely-used-heart-drug-tied-to-dementia-risk%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Dr. Robert McBane – Vascular Medicine, Mayo Clinic
From: Mayo Clinic http://redirect.viglink.com?u=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DoBuJ4PlPEt8&key=ddaed8f51db7bb1330a6f6de768a69b8
ADAF grant program rewards those who provide access to care, dental homes
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.ada.org%2Fen%2Fpublications%2Fada-news%2F2016-archive%2Fmay%2Fadaf-grant-program-rewards-those-who-provide-access-to-care&key=ddaed8f51db7bb1330a6f6de768a69b8
FDA issues final rule on all tobacco products
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.ada.org%2Fen%2Fpublications%2Fada-news%2F2016-archive%2Fmay%2Ffda-issues-final-rule-on-all-tobacco-products&key=ddaed8f51db7bb1330a6f6de768a69b8
FDA Bans Underage E-Cigarette Sales
The FDA will bar sales of e-cigarettes, cigars, and hookah tobacco to anyone under 18. WebMD has the details.
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fsmoking-cessation%2Fnews%2F20160505%2Fban-underage-electronic-cigarette-sales%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
"Modern Family" actor on body image, mental health
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Fmodern-family-actor-reid-ewing-on-body-image-mental-health-healing%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Is There Gunk On Your Greens? 4 Things To Know About The Listeria Recall
The FDA issued a big recall of frozen foods this week. Here’s what you need to know about the nasty bug that’s causing all the problems.
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fhealth-insurance%2F20160505%2Fis-there-gunk-on-your-greens-4-things-to-know-about-the-listeria-recall%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Robot surgeons one step closer to reality
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Frobot-surgeon-stitches-tissue-by-itself%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Chinese boy born with 31 fingers and toes
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Ffamily-seeks-help-for-chinese-boy-born-with-31-fingers-and-toes-polydactylism%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Stay Lean, Live Longer
Researchers found slimmest people had lowest chances of dying in two studies
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fdiet%2F20160505%2Fstay-lean-live-longer%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Race May Influence Risk for Irregular Heart Beat
Whites with heart failure more likely to develop atrial fibrillation, research finds
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fheart%2Fnews%2F20160505%2Frace-may-influence-risk-for-irregular-heart-beat%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Sleep Apnea May Raise Heart Risks in These People
Study found the combo was linked to raised odds of irregular heartbeat
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fsleep-disorders%2Fsleep-apnea%2Fnews%2F20160505%2Fsleep-apnea-may-raise-heart-risks-in-people-with-pacemakers%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Lung Cancer Surgery Worthwhile for Older Patients
Study found those 65 and older survived longer when they had operation
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Flung-cancer%2Fnews%2F20160505%2Flung-cancer-surgery-worthwhile-for-older-patients%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
4 Things To Know About The Listeria Recall
The FDA issued a big recall of frozen foods this week. Here’s what you need to know about the nasty bug that’s causing all the problems.
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Ffood-recipes%2Ffood-poisoning%2F20160505%2Fis-there-gunk-on-your-greens-4-things-to-know-about-the-listeria-recall%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
New video shines spotlight on Ethics Code’s 150th anniversary
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.ada.org%2Fen%2Fpublications%2Fada-news%2F2016-archive%2Fmay%2Fnew-video-shines-spotlight-on-ethics-codes-150th-anniversary&key=ddaed8f51db7bb1330a6f6de768a69b8
Hep C Now Leading U.S. Infectious Disease Killer
CDC notes that nearly 20,000 Americans died in 2014 from the widespread, but treatable, illness
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.webmd.com%2Fhepatitis%2Fnews%2F20160504%2Fhepatitis-c-now-leading-infectious-disease-killer-in-us%3Fsrc%3DRSS_PUBLIC&key=ddaed8f51db7bb1330a6f6de768a69b8
Dirty scopes linked to more hospital deaths
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Fdirty-scopes-linked-to-more-hospital-deaths%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Blue Bell recalls mislabeled ice cream over allergy concerns
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Fblue-bell-recalls-mislabeled-ice-cream-over-allergy-concerns%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
FDA unveils new regulations on e-cigarettes
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.cbsnews.com%2Fnews%2Ffda-e-cigarettes-new-regulations%2F&key=ddaed8f51db7bb1330a6f6de768a69b8
Diabetes drug pioglitazone could get personal: Neither panacea, nor peril
When I was in training, one of my beloved mentors declared, “I never use a drug until it’s been on the market for 20 years.” I was young enough then that I couldn’t fathom being a doctor for 20 years, let alone waiting two decades to use a new drug. As my career has progressed, I’ve seen many new drugs released to the market. Some of them are truly miraculous, bringing people longer, healthier, and more productive lives. Many of them have not withstood the test of time. More than a few have even been taken off the market. Even though the Food and Drug Administration diligently reviews each new medicine before it’s approved for use, we often learn much more about a drug after its release into the general population.
I reflected on that memory when I read a recent editorial in The New England Journal of Medicine (NEJM) about insulin resistance. In his editorial, the author tells us of the “long, strange trip” of a class of medications called thiazolidinediones, which help people who have type 2 diabetes or pre-diabetes to be more sensitive to the insulin that they make in their bodies. (Many diabetes medications work by helping the body lower its resistance to insulin in different ways.)
When they were first released, these medicines were widely accepted and adopted. We do, after all, have an epidemic of obesity and diabetes in the United States, and they seemed to work very well for people. They seemed a great alternative to insulin, which has to be injected. Then, after about 6 years on the market, these drugs began to be linked to liver disease and congestive heart failure — and maybe even cancer. Even though longer-term studies did not show that there was a definite risk of heart attack or cancer, these drugs became unpopular and fell into disuse. We were not willing to take a chance with our patients when we had other good options.
And yet, some researchers continued to wonder if there was any safe role for these very potent medications with their many positive effects, despite the concerns. The same NEJM issue as the editorial referenced above also contains a study that showed that certain carefully selected patients might, in fact, have fewer strokes if they took a medication called pioglitazone, which is in the thiazolidinedione class of medicines. Interestingly, the patients in this trial were already on extremely comprehensive stroke prevention regimens — and still they decreased their risk of a future stroke by 24%. These patients, all of whom were at risk of developing diabetes, had a slower rate of progression to diabetes as well.
What grabbed me about this story? First, it would seem that the drugs in question are neither panacea nor pariah. Pioglitazone, in fact, might a very good drug to prevent stroke in a very select population.
But, can we define that select population? That might be the most interesting tale of the past decades. Twenty years ago, we could only guess, based on certain characteristics of a patient, whether a medication would be effective. Today, we know certain people’s genetics make them better candidates for certain medications than other people. We are close to being able to tailor a medication to the patient at the level of his or her genes. When we are able to do this in an effective, safe, and efficient way, we will be able to deliver truly personalized medicine. As a clinician, I find this truly exciting. It would be wonderful to say to a patient, “This drug might have the following side effects — but I know they won’t affect you!”
My mentor may well have been right that it takes 20 years to know how a drug works and for whom it will work. He would not be surprised by the strange story of thiazolidinediones. He would undoubtedly be overjoyed by the idea that the past 20 years of laboratory and clinical research has brought us that much closer to truly personalized care.
Related Post:
The post Diabetes drug pioglitazone could get personal: Neither panacea, nor peril appeared first on Harvard Health Blog.
From: Lori Wiviott Tishler, MD, MPH http://redirect.viglink.com?u=http%3A%2F%2Fwww.health.harvard.edu%2Fblog%2Fdiabetes-drug-pioglitazone-get-personal-neither-panacea-peril-201605059574&key=ddaed8f51db7bb1330a6f6de768a69b8
Obama Administration to Help Five Small Communities Revitalize Downtowns through Broadband Service
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.usda.gov%2Fwps%2Fportal%2Fusda%2Fusdahome%3Fcontentid%3D2016%2F05%2F0104.xml%26amp%3Bcontentidonly%3Dtrue&key=ddaed8f51db7bb1330a6f6de768a69b8
ADA members campaign for Congress
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.ada.org%2Fen%2Fpublications%2Fada-news%2F2016-archive%2Fmay%2Fada-members-campaign-for-congress&key=ddaed8f51db7bb1330a6f6de768a69b8
USDA Announces Conservation Reserve Program Results
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.usda.gov%2Fwps%2Fportal%2Fusda%2Fusdahome%3Fcontentid%3D2016%2F05%2F0105.xml%26amp%3Bcontentidonly%3Dtrue&key=ddaed8f51db7bb1330a6f6de768a69b8
Fitness ball exercises: How-to video collection
From: http://redirect.viglink.com?u=http%3A%2F%2Fwww.mayoclinic.org%2Fhealthy-lifestyle%2Ffitness%2Fin-depth%2Ffitness-ball%2Fart-20046053&key=ddaed8f51db7bb1330a6f6de768a69b8