04/01/16

Friday, April 1, 2016

Married couple commit to finding cure for wife's disease

When Sonia Vallabh was diagnosed with a rare incurable disease five years ago, she and her husband decided to take matters into their own hands

From: http://www.cbsnews.com/videos/married-couple-commit-to-finding-cure-for-wifes-disease/

Newlyweds become medical researchers to find cure for wife's disease

Sonia Vallabh and her husband Eric Minikel had no background in medicine, but a grim prognosis forced them to take matters into their own hands

From: http://www.cbsnews.com/news/on-the-road-newlyweds-become-research-scientist-to-find-cure-for-wifes-disease/

U.S. summit focuses on fighting mosquito-borne Zika

Hundreds of federal, state and local health officials attended the Atlanta meeting focused on Zika monitoring, mosquito control, and protections for pregnant women

From: http://www.cbsnews.com/news/us-summit-focuses-on-fighting-mosquito-borne-zika/

University disavows chocolate milk, concussions study

After backlash for a questionable press release, the University of Maryland backtracked on findings linking chocolate milk to concussion recovery

From: http://www.cbsnews.com/news/university-disavows-chocolate-milk-concussions-study/

Zika Coming: Some of U.S. Lacks Mosquito Control

Mosquitoes carrying the Zika virus could be a problem in most states this year. At the same time, nearly half the country lacks any kind of mosquito control.

From: http://www.webmd.com/news/20160401/zika-coming-some-us-lacks-mosquito-control?src=RSS_PUBLIC

FDA Suggests Arsenic Limit in Infant Rice Cereal

The element occurs naturally in soil and water; rice plants absorb it more than other crops, agency says

From: http://www.webmd.com/children/news/20160401/fda-suggests-limit-for-arsenic-in-infant-rice-cereal?src=RSS_PUBLIC

Could ADHD Drugs Lower Kids' Bone Density?

Study raises questions about bone health of young people taking meds like Ritalin and Adderall

From: http://www.webmd.com/add-adhd/childhood-adhd/news/20160401/could-adhd-drugs-lower-kids-bone-density?src=RSS_PUBLIC

Coffee's latest health perk?

Whether its an espresso or decaf, the more coffee you drink, the lower the risk for colon cancer might be, new research suggests

From: http://www.cbsnews.com/news/coffees-latest-health-perk-may-be-a-lower-risk-for-colon-cancer/

A baby's BMI may predict early obesity

Pediatricians should measure body mass index (BMI) during infant well-child visits, study authors urge

From: http://www.cbsnews.com/news/a-babys-bmi-may-predict-early-obesity/

Why I Am a Diabetes Advocate: Chuck Malloy

This week, advocates from around the country will convene in Washington, D.C., for the biannual American Diabetes Association® Capitol Hill Advocacy Day. What does it mean to be a Diabetes Advocate? Let’s hear from Association volunteer Chuck Malloy, who will be joining us from Idaho.

Call it the grace of God, or dumb luck. Either way, I will take it.

When a person’s health starts to go downhill in his or her 50s, it often serves as a prelude to an early death. My health was on a free-fall during my early 50s—and there was no question that my life was in peril.

During my time as an editorial writer with the Idaho Statesman from 1999 to 2003, I remember frequently going to work with the feeling that my head was in a fog. It wasn’t anything that anyone noticed, and I attributed my situation to heavy stress and long work hours.

As it turned out, this “silent killer” also called type 2 diabetes was taking its cruel toll. In retrospect, it was amazing that I could write anything that made sense, let along thought-provoking editorials for a capital city newspaper. Meanwhile, the effects of diabetes were eating at me in other ways. I noticed my eyesight was deteriorating over time and, finally, in December 2003, I had to leave the paper because I couldn’t see well enough to read letters on my desk.

Blindness was only the beginning of my complications. The “fog” that I was feeling in my head probably was the result of diabetes clogging my heart. Within a year of leaving the Statesman, a cardiologist told me I was a prime candidate for keeling over at any moment. Shortly after that, I had a five-way bypass surgery that essentially reconstructed my heart.

But this is not a story of gloom and doom. It’s one of personal triumph and beating the odds—with a lot of help from a lot of smart, and compassionate, medical professionals. Of course, they could not have had success without the technical advances in heart surgery procedures and diabetes care. I owe my life to agencies such as the Centers for Disease Control and Prevention and the National Institute of Health, which have been game-changers for millions of Americans battling this horrific disease.

I am now 65 years old and feeling better than I have in decades. My eyesight has recovered completely, with the help of a lot of procedures, and my heart is strong and healthy. My cardiologist told me recently, “The best thing I can do for you is stay out of your way.” My golf game is almost where it was 30 years ago. If you assume that bogey is the “new” par, as I do, then I’m breaking par on a regular basis.

More importantly, my diabetes is under good control. A 7.4 A1C isn’t perfect, but it’s a lot better than the 9.5 readings I had been getting. Doctors are no longer seeing black helicopters when they read my medical chart.

The moral of this story is that diabetes is not a death sentence. It can be managed, and I am living proof that many of the horrible effects can be reversed.

I am blessed and it is a privilege for me to tell my congressional delegation, and other members of Congress, that continued funding for diabetes research and prevention is money well spent.

Just because you’re not joining Chuck on the Hill doesn’t mean you can’t help. Anyone who is affected by diabetes can be an advocate and take part Capitol Hill Advocacy Day from afar.

Please sign our petition to Congress at http://stopdiabetes.com/petition. Together, we can win this battle!

The Association also asks that you join our Thunderclap and dedicate your social media status to help spread the word about our advocacy efforts. By inviting your friends and family to participate we can ignite a dialogue about the importance of preventing, treating and curing diabetes.

From: American Diabetes Association http://diabetesstopshere.org/2016/04/01/diabetes-advocate-chuck/

Is Seniors' Dental Health Tied to Mental Health?

Declines in one seem to mirror declines in the other, but cause-and-effect isn't clear, study says

From: http://www.webmd.com/oral-health/news/20160401/is-seniors-dental-health-tied-to-mental-health?src=RSS_PUBLIC

A New Health Perk for Coffee Drinkers?

The brew, in any form, might cut colon cancer risk; the more you drink, the lower the risk, study suggests

From: http://www.webmd.com/colorectal-cancer/news/20160401/a-new-health-perk-for-coffee-drinkers?src=RSS_PUBLIC

Infant's BMI May Predict Early Childhood Obesity

Pediatricians should assess body mass index beginning at 6 months, researchers advise

From: http://www.webmd.com/parenting/baby/news/20160401/infants-bmi-may-predict-early-childhood-obesity-study-says?src=RSS_PUBLIC

New positive case of Ebola virus disease confirmed in Liberia

Liberian health authorities convened an emergency meeting today with key partners to coordinate and plan a rapid response to the new positive case of Ebola virus disease.

From: http://www.who.int/entity/mediacentre/news/statements/2016/liberia-ebola/en/index.html

Just the Facts - April 4

By 2015, the percentage of female dentists working in dentistry was 29 percent, up from 20 percent in 2005.

From: http://www.ada.org/en/publications/ada-news/2016-archive/april/just-the-facts-april-4

Snapshots of American Dentistry - April 4

Dentists working in dentistry

From: http://www.ada.org/en/publications/ada-news/2016-archive/april/snapshots-of-american-dentistry-april-4

More of the global population now obese than underweight

If trends persist, around a fifth of adults worldwide will be obese by 2025, researcher say

From: http://www.cbsnews.com/news/more-of-the-global-population-now-obese-than-underweight/

Dangerous new "Banana Peel Challenge" has teens wiping out for likes

Yet another viral trend has people's judgment slipping in the quest for social media stardom

From: http://www.cbsnews.com/news/dangerous-viral-banana-peel-challenge-has-teens-wiping-out-for-social-media-likes/

Surgeons save siblings with multi-organ transplants, 5 years apart

Five years after the transplant surgeons saved the life of an infant girl, they were called upon again to save the life of her younger brother

From: http://www.cbsnews.com/news/university-of-miami-surgeons-save-siblings-with-multi-organ-transplants/

Mayo Clinic Minute: Go Inside the Brain Bank

From: Mayo Clinic http://www.youtube.com/watch?v=x1dgfg4eqYM

Soy Protein Compared with Milk Protein in a Western Diet Increases Gut Microbial Diversity and Reduces Serum Lipids in Golden Syrian Hamsters [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Diet is a major factor influencing the composition and metabolic activity of the gut microbiota.

Objective: This study investigated the effect of soy compared with dairy protein on the gut microbiota of hamsters to determine whether changes in microbiota could account for soy protein's lipid lowering properties.

Methods: Thirty-two 6- to 8-wk-old, male Golden Syrian hamsters were fed a Western diet containing 22% (%wt) milk protein isolate (MPI) as the single protein source for 3 wk followed by 6 wk of one of 4 diets containing either [22% protein (%wt)]: MPI, soy protein concentrate (SPC), partially hydrolyzed soy protein isolate (SPI1), or intact soy protein isolate. Serum lipids, hepatic gene expression, and gut microbial populations were evaluated.

Results: Serum total and LDL-cholesterol concentrations were lower in the SPC-fed group (183 ± 9.0 and 50 ± 4.2 mg/dL, respectively) than in the MPI group (238 ± 8.7 and 72 ± 3.9 mg/dL, respectively) (P < 0.05). Triglyceride (TG) concentrations were lower (P < 0.05) in the SPI1-fed group (140 ± 20.8 mg/dL) than in the MPI-fed group (223 ± 14.2 mg/dL). VLDL and non-HDL-cholesterol concentrations were lower (by 40–49% and 17–33%, respectively) in all soy-fed groups than in the MPI-fed group (P < 0.05). Sequencing of the 16S ribosomal RNA gene revealed greater microbial diversity in each soy-fed group than in the MPI-fed group (P < 0.05). The cholesterol- and TG-lowering effect of soy protein was associated with higher expression of 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr), lanosterol synthase (Lss), and farnesyl-diphosphosphate farnesyl-transferase 1 (Fdft1) (1.6–2.5-fold higher), and lower steroyl-CoA desaturase-1 (Scd1) expression (37–46% lower) in all soy-fed groups (P < 0.05) compared with the MPI-fed group. Gut microbes that showed significant diet differences were significantly correlated ( = –0.68 to 0.65, P < 0.05) with plasma lipids and hepatic gene expression.

Conclusion: Dietary protein sources in male Golden Syrian hamsters fed a Western diet affect the gut microbiota, and soy protein may reduce lipogenesis through alterations of the gut microbial community.

From: Butteiger, D. N., Hibberd, A. A., McGraw, N. J., Napawan, N., Hall-Porter, J. M., Krul, E. S. http://jn.nutrition.org/cgi/content/short/146/4/697?rss=1

Short-Term Vitamin B-6 Restriction Does Not Affect Plasma Concentrations of Hydrogen Sulfide Biomarkers Lanthionine and Homolanthionine in Healthy Men and Women [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Suboptimal vitamin B-6 status is associated with increased cardiovascular disease risk, although the mechanism is unknown. The synthesis of the vasodilator hydrogen sulfide occurs through side reactions of the transsulfuration enzymes cystathionine β-synthase and cystathionine -lyase, with pyridoxal 5'-phosphate as a coenzyme. Two proposed hydrogen sulfide biomarkers, lanthionine and homolanthionine, are produced concurrently.

Objective: To determine whether hydrogen sulfide production is reduced by vitamin B-6 deficiency, we examined the relations between plasma concentrations of lanthionine and homolanthionine, along with other components of the transsulfuration pathway (homocysteine, cystathionine, and Cys), in a secondary analysis of samples from 2 vitamin B-6 restriction studies in healthy men and women.

Methods: Metabolite concentrations were measured in plasma from 23 healthy adults (12 men and 11 women) before and after 28-d controlled dietary vitamin B-6 restriction (0.37 ± 0.04 mg/d). Vitamin B-6 restriction effects on lanthionine and homolanthionine concentrations were assessed. Associations between hydrogen sulfide biomarkers, transsulfuration metabolites, and functional indicators of vitamin B-6 deficiency were analyzed by linear regression.

Results: Preprandial plasma lanthionine and homolanthionine concentrations ranged from 89.0 to 372 nmol/L and 5.75 to 32.3 nmol/L, respectively, in healthy adults. Mean lanthionine and homolanthionine concentrations were not affected by vitamin B-6 restriction (P < 0.66), with marked heterogeneity of individual responses. After restriction, homolanthionine was positively associated with functional indicators of vitamin B-6 deficiency, which differed from hypothesized negative associations. Plasma lanthionine was positively correlated with the concentration of its precursor, Cys, before (R² = 0.36; P = 0.002) and after (R² = 0.37; P = 0.002) restriction. Likewise, homolanthionine concentration was positively correlated with its precursor homocysteine, but only in vitamin B-6 adequacy (R² = 0.41; P < 0.001).

Conclusions: The resiliency of plasma lanthionine and homolanthionine concentrations after short-term vitamin B-6 restriction suggests a minimal effect of moderate vitamin B-6 deficiency on hydrogen sulfide production. Additional research is needed to better understand the metabolism and disposal of these biomarkers in humans. This study was registered at clinicaltrials.gov as NCT00877812.

From: DeRatt, B. N., Ralat, M. A., Gregory, J. F. http://jn.nutrition.org/cgi/content/short/146/4/714?rss=1

Folic Acid Supplementation of Female Mice, with or without Vitamin B-12, before and during Pregnancy and Lactation Programs Adiposity and Vascular Health in Adult Male Offspring [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: The developmental origins of health and disease theory suggest that disturbances in the fetal and early postnatal environment contribute to chronic adulthood diseases, such as type 2 diabetes and cardiovascular disease. Greater adiposity and insulin resistance have been reported in children of women with high erythrocyte folate but poor vitamin B-12 status during pregnancy. The mechanisms underlying this relation are not known.

Objective: The objective of this study was to investigate the effects of maternal supplemental folic acid, with or without vitamin B-12, on adiposity, glucose homeostasis, and vascular health in adult male offspring mice.

Methods: Female C57BL/6J mice were fed a control diet (M-CON, 2 mg folic acid/kg, 50 μg vitamin B-12/kg) or a folic acid–supplemented diet with [10 mg folic acid/kg, 50 μg vitamin B-12/kg (SFA+B12)] or without [10 mg folic acid/kg, no vitamin B-12 (SFA-B12)] vitamin B-12 for 6 wk before mating and during pregnancy and lactation. The offspring were weaned onto a control diet (16% energy from fat) or a western diet (45% energy from fat) until 23 wk of age. The effects of maternal diet on adiposity, vascular function, and glucose tolerance were assessed in 6 groups of adult male offspring: control diet-fed M-CON, SFA+B12, and SFA-B12 and western diet-fed M-CON, SFA+B12, and SFA-B12.

Results: Control and western diet-fed SFA-B12 and SFA+B12 offspring had smaller visceral and subcutaneous adipose tissue than M-CON offspring (P < 0.05). Control SFA-B12 and SFA+B12 offspring had lower serum total adiponectin and vitamin B-12 concentrations and lower NADPH oxidase 2 expression in aorta compared with M-CON offspring (P < 0.05). These effects were not observed in western diet-fed offspring.

Conclusions: Folic acid supplementation of female mice before and during pregnancy and lactation, with or without dietary vitamin B-12, affects adult male offspring adiposity, vascular function, and one-carbon metabolism in those fed a control diet but not a western diet.

From: Aleliunas, R. E., Aljaadi, A. M., Laher, I., Glier, M. B., Green, T. J., Murphy, M., Miller, J. W., Devlin, A. M. http://jn.nutrition.org/cgi/content/short/146/4/688?rss=1

Dietary Protein Requirement of Men >65 Years Old Determined by the Indicator Amino Acid Oxidation Technique Is Higher than the Current Estimated Average Requirement [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Flavanol-Enriched Cocoa Powder Alters the Intestinal Microbiota, Tissue and Fluid Metabolite Profiles, and Intestinal Gene Expression in Pigs [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Consumption of cocoa-derived polyphenols has been associated with several health benefits; however, their effects on the intestinal microbiome and related features of host intestinal health are not adequately understood.

Objective: The objective of this study was to determine the effects of eating flavanol-enriched cocoa powder on the composition of the gut microbiota, tissue metabolite profiles, and intestinal immune status.

Methods: Male pigs (5 mo old, 28 kg mean body weight) were supplemented with 0, 2.5, 10, or 20 g flavanol-enriched cocoa powder/d for 27 d. Metabolites in serum, urine, the proximal colon contents, liver, and adipose tissue; bacterial abundance in the intestinal contents and feces; and intestinal tissue gene expression of inflammatory markers and Toll-like receptors (TLRs) were then determined.

Results: O-methyl-epicatechin-glucuronide conjugates dose-dependently increased (P < 0.01) in the urine (35- to 204-fold), serum (6- to 186-fold), and adipose tissue (34- to 1144-fold) of pigs fed cocoa powder. The concentration of 3-hydroxyphenylpropionic acid isomers in urine decreased as the dose of cocoa powder fed to pigs increased (75–85%, P < 0.05). Compared with the unsupplemented pigs, the abundance of Lactobacillus species was greater in the feces (7-fold, P = 0.005) and that of Bifidobacterium species was greater in the proximal colon contents (9-fold, P = 0.01) in pigs fed only 20 or 10 g cocoa powder/d, respectively. Moreover, consumption of cocoa powder reduced TLR9 gene expression in ileal Peyer’s patches (67–80%, P < 0.05) and mesenteric lymph nodes (43–71%, P < 0.05) of pigs fed 2.5–20 g cocoa powder/d compared with pigs not supplemented with cocoa powder.

Conclusion: This study demonstrates that consumption of cocoa powder by pigs can contribute to gut health by enhancing the abundance of Lactobacillus and Bifidobacterium species and modulating markers of localized intestinal immunity.

From: Jang, S., Sun, J., Chen, P., Lakshman, S., Molokin, A., Harnly, J. M., Vinyard, B. T., Urban, J. F., Davis, C. D., Solano-Aguilar, G. http://jn.nutrition.org/cgi/content/short/146/4/673?rss=1

The Microbiome, Intestinal Function, and Arginine Metabolism of Healthy Indian Women Are Different from Those of American and Jamaican Women [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Indian women have slower arginine flux during pregnancy compared with American and Jamaican women. Arginine is a semi-essential amino acid that becomes essential during periods of rapid lean tissue deposition. It is synthesized only from citrulline, a nondietary amino acid produced mainly in the gut. The gut is therefore a key site of arginine and citrulline metabolism, and gut microbiota may affect their metabolism.

Objective: The objective of this study was to identify differences in the gut microbiota of nonpregnant American, Indian, and Jamaican women and characterize the relations between the gut microbiota, gut function, and citrulline and arginine metabolism.

Methods: Thirty healthy American, Indian, and Jamaican women (n = 10/group), aged 28.3 ± 0.8 y, were infused intravenously with [guanidino-¹⁵N₂]arginine, [5,5-²H₂]citrulline, and [¹⁵N₂]ornithine and given oral [U-¹³C₆]arginine in the fasting and postprandial states. Fecal bacterial communities were characterized by 16S rRNA gene sequencing.

Results: In the fasting state, Indian women had lower citrulline flux than did American and Jamaican women [7.0 ± 0.4 compared with 9.1 ± 0.4 and 8.9 ± 0.2 μmol ⋅ kg fat-free mass (FFM)^–1 ⋅ h^–1, P = 0.01] and greater enteral arginine conversion to ornithine than did American women (1.4 ± 0.11 compared with 1.0 ± 0.08 μmol ⋅ kg FFM^–1 ⋅ h^–1, P = 0.04). They also had lower mannitol excretion than American and Jamaican women (154 ± 37.1 compared with 372 ± 51.8 and 410 ± 39.6 mg/6 h, P < 0.01). Three dominant stool community types characterized by increased abundances of the genera Prevotella, Bacteroides, and Bacteroides with Clostridium were identified. Indian women had increased mean relative abundances of Prevotella (42%) compared to American and Jamaican women (7% and < 1%, P = 0.03) which were associated with diet, impaired intestinal absorptive capacity, and arginine flux.

Conclusions: These findings suggest that dysregulated intestinal function and a unique gut microbiome may contribute to altered arginine metabolism in Indian women.

From: Kao, C. C., Cope, J. L., Hsu, J. W., Dwarkanath, P., Karnes, J. M., Luna, R. A., Hollister, E. B., Thame, M. M., Kurpad, A. V., Jahoor, F. http://jn.nutrition.org/cgi/content/short/146/4/706?rss=1

A monthly shot for opioid addiction: An option for some

On average, 44 people in the United States die every day from an overdose of opioid prescription painkillers. These drugs — such as Vicodin, Percocet, codeine, and morphine — reduce the brain’s recognition of pain by binding to certain receptors in the body. With continued use, a person can develop a physical dependence on these drugs, such that withdrawal symptoms occur if the drug is stopped. These drugs can also cause a “high.” Both of these effects contribute to addiction — that is, the loss of control around the use of a drug, even though it causes harm to the person. Addiction to opioid painkillers is the biggest risk factor for heroin addiction.

Treatment options

Treatment for opioid addiction includes detoxification (or “detox”) programs. However, this alone is often not enough; many people will relapse and use again without additional treatment such as counseling and long-term medications. There are three FDA-approved long-term medications for treating opioid addiction:

Methadone. This is an “agonist” drug that binds to the body’s opioid receptors and activates these receptors as the opioid drug would. It is offered at certified treatment facilities, usually as a liquid medication taken every day.
Buprenorphine. This is a “partial agonist” drug that binds to the body’s opioid receptors and partly activates them. It is prescribed by trained physicians, most often as a combination pill with antagonist naloxone (Suboxone), and is taken every day.
Naltrexone (Vivitrol). This is an “antagonist” that binds to the opioid receptors but does not activate them, and thus blocks the action of other opioid drugs. It can be prescribed by any health care provider who is licensed to write prescriptions, and is available as either a daily pill or a monthly injection.

More on naltrexone

When naltrexone is given as a pill every day, many people have a hard time sticking to it and drop out of treatment.

Vivitrol is a long-acting form of naltrexone which is given as an injection once a month. Scientists are also working on similar longer-acting implants. Vivitrol was approved by the FDA for alcohol dependence in 2006 (as it has been shown to reduce alcohol cravings and heavy drinking), and for opioid dependence in 2010.

In one 6-month study, participants were treated with monthly injections along with counseling. Though many participants did drop out of treatment, 36% of those in the injection treatment group succeeded in total abstinence from opioids, as compared with 23% in those treated with a placebo injection.

There have been no studies directly comparing the three long-term treatments with each other. However, it appears that individuals are more likely to stick to treatment and avoid other opioid use with the agonist drugs methadone and buprenorphine. Vivitrol may be more appropriate for individuals who

have had no success with the agonist treatments
have a milder addiction and are highly motivated to quit
prefer to not take agonist treatments, or cannot do so because of legal or job requirements
have difficulty committing to taking a medication every day
face an increased risk for relapse, such as right after detoxification or during a time of stress.

Vivitrol side effects

Side effects of Vivitrol may include nausea (temporary), headache, and dizziness. There may be serious reactions at the injection site, especially if not given into the muscle with a specially designed needle, as recommended. Other reported side effects include liver test abnormalities, depression, and an allergic pneumonia.

If someone relapses and starts to use opioid drugs again, they will not experience the same “high” since the antagonist is blocking the receptor from the opioids. However, using very high doses of opioids to try to overcome the blocking effects of Vivitrol may cause overdose and death.

Also, the risk of overdose or death is high in those who stop Vivitrol and then reuse opioid drugs. Individuals may be unaware of their loss of tolerance while on Vivitrol, and misjudge the effects of even a smaller amount of opioids than what was previously used.

It is recommended that those using Vivitrol should always carry some form of medic alert in case of emergencies.

How is Vivitrol given?

There are increasing numbers of clinics and doctors’ offices that offer Vivitrol injection. Patients must be off all opioids for 7-10 days and alcohol for at least 24 hours prior to starting naltrexone, otherwise severe withdrawal symptoms might occur. Giving a short-acting antagonist (oral naltrexone or naloxone) prior to starting the injections to confirm no withdrawal symptoms can shorten the wait time for starting the long-acting injections. Also, trials have been promising using slowly increasing doses of oral naltrexone combined with slowly decreasing doses of buprenorphine to help shorten the wait time to Vivitrol treatment.

The post A monthly shot for opioid addiction: An option for some appeared first on Harvard Health Blog.

From: Wynne Armand, MD http://www.health.harvard.edu/blog/a-monthly-shot-for-opioid-addiction-an-option-for-some-201604019364

NHL team dentist champions mouthguards

Dr. Thomas Long, a lifelong ice hockey player, didn't rise to the ranks of the National Hockey League as an athlete, but he still contributes to professional hockey players' success because he's a dentist.

From: http://www.ada.org/en/publications/ada-news/2016-archive/april/nhl-team-dentist-champions-mouthguards

USDA Announces over $90 Million Available to Support Local Food Systems, Specialty Crop Producers

WASHINGTON, April 1, 2016 – The U.S. Department of Agriculture (USDA) today announced the availability of more than $90 million in competitive grants to help strengthen local and regional food systems, develop new market opportunities for producers, and support farmers growing fruits, vegetables, tree nuts, flowers and nursery crops (known collectively as specialty crops).

From: http://www.usda.gov/wps/portal/usda/usdahome?contentid=2016/04/0083.xml&contentidonly=true

Free content from the Journal of Prosthodontics until April 30

To mark National Prosthodontics Awareness week, April 3-9, the Journal of Prosthodontics is offering access to select peer-reviewed research at no cost through 2016. Access is available now.

From: http://www.ada.org/en/publications/ada-news/2016-archive/april/free-content-from-the-journal-of-prosthodontics-until-april-30

Friday, April 1, 2016

Treatment options

More on naltrexone

Vivitrol side effects

How is Vivitrol given?

Related Post: