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Friday, October 7, 2016
10/7 Hurricane Matthew weakens, but still dangerous; Floridians faced hurricane danger with compassion
From: http://www.cbsnews.com/videos/107-hurricane-matthew-weakens-but-still-dangerous-floridians-faced-hurricane-danger-with-compassion/
Hurricane help: Best ways to lend a hand after the storm
From: http://www.cbsnews.com/news/hurricane-help-best-ways-to-lend-a-hand-after-the-storm/
More and more Americans suffer from this painful condition
From: http://www.cbsnews.com/news/more-americans-suffer-from-severe-joint-pain/
Actor Gabrielle Union Is on a Breast Health Mission
Inspired by the loss of a close pal, she empowers women to get cancer screenings.
From: http://www.webmd.com/breast-cancer/features/gabrielle-union-breast-health?src=RSS_PUBLIC
ADA Foundation offers relief to dentists affected by Hurricane Matthew
From: http://www.ada.org/en/publications/ada-news/2016-archive/october/ada-foundation-offers-relief-to-dentists-affected-by-hurricane-matthew
Minimally Disruptive Medicine Workshop 2016: Shared Decision Making
From: Mayo Clinic http://www.youtube.com/watch?v=1tuZrEvI2BQ
Minimally Disruptive Medicine Workshop 2016: The Patient Revolution
From: Mayo Clinic http://www.youtube.com/watch?v=iDMU6-cF7MA
Minimally Disruptive Medicine 2017 Workshop: Patient Perspective
From: Mayo Clinic http://www.youtube.com/watch?v=hb-RSaatdmo
Do Middle Ear Infections Have a Genetic Link?
They're the No. 1 reason kids get antibiotics, and finding could point to better treatments, researchers say
From: http://www.webmd.com/cold-and-flu/ear-infection/news/20161007/study-suggests-genetic-link-to-middle-ear-infections?src=RSS_PUBLIC
Panel discusses challenges facing older adults seeking oral health care
From: http://www.ada.org/en/publications/ada-news/2016-archive/october/panel-discusses-challenges-facing-older-adults-seeking-oral-health-care
ADA presents awards honorary memberships to trio
From: http://www.ada.org/en/publications/ada-news/2016-archive/october/ada-presents-awards-honorary-memberships-to-trio
Why you should order that hoppy beer
From: http://www.cbsnews.com/news/why-you-should-order-that-hoppy-beer/
Why U.S. life expectancy lags behind other wealthy nations
From: http://www.cbsnews.com/news/us-life-expectancy-lags-behind-other-wealthy-nations/
Males born via fertility treatment may have weaker sperm
From: http://www.cbsnews.com/news/males-born-via-fertility-treatment-may-have-weaker-sperm/
Woman has baby with mom's womb, says it's "science fiction"
From: http://www.cbsnews.com/news/woman-gives-birth-to-baby-with-moms-womb-says-its-science-fiction/
Lil' Luxuries Infant Bathtubs Recalled
Lil' Luxuries Infant Bathtubs Recalled
From: http://www.webmd.com/parenting/baby/news/20161007/infant-bathtub-recall?src=RSS_PUBLIC
Fertility Treatment May Mean Weaker Sperm in Males
Procedure that injects sperm into egg was linked with lower quantity and quality of offspring's sperm
From: http://www.webmd.com/infertility-and-reproduction/news/20161007/males-conceived-via-fertility-treatment-may-have-weakened-sperm-study?src=RSS_PUBLIC
U.S. Life Expectancy Trails Other Wealthy Nations
Diabetes, drugs and guns contribute to disappointing statistics in new global report
From: http://www.webmd.com/healthy-aging/news/20161006/us-life-expectancy-lags-behind-other-wealthy-nations?src=RSS_PUBLIC
New Clues to Age-Related Hearing Loss
Older people's brains have a harder time processing speech, researchers suggest
From: http://www.webmd.com/healthy-aging/news/20161006/new-clues-to-age-related-hearing-loss?src=RSS_PUBLIC
Number of Americans With Severe Joint Pain Rising
CDC tally estimates that close to 15 million people now live with this discomfort
From: http://www.webmd.com/arthritis/news/20161006/number-of-americans-with-severe-joint-pain-keeps-rising?src=RSS_PUBLIC
Medications Help Limit Breast Cancer's Spread
6-year study finds follow-up therapy cuts survivors' risk for cancer in the other breast
From: http://www.webmd.com/breast-cancer/news/20161006/more-evidence-tamoxifen-other-meds-help-limit-breast-cancers-spread?src=RSS_PUBLIC
What's Rapunzel syndrome? Definitely no fairy tale
From: http://www.cbsnews.com/news/whats-rapunzel-syndrome-definitely-no-fairy-tale-hairball-disorder/
Many ways to lower cholesterol will reduce heart disease risk
Several contemporary clinical trials have shown that cholesterol-lowering statin drugs reduce the risk of heart attacks in patients with coronary artery disease. This compelling body of evidence has led to the question of whether other drugs that lower cholesterol also reduce heart attacks. Older studies had certainly shown this, though these studies were from an era prior to widespread statin use. A recent study showed that in patients with a mild heart attack, adding ezetimibe — a drug that interferes with cholesterol absorption from the intestines — to a statin reduced cardiovascular risk compared with a statin alone.
Now, a carefully done meta-analysis synthesizes all the studies to date and provides some new insights. A meta-analysis is a way of combining data from many studies over several years and analyzing the data to provide a bottom-line message. This particular meta-analysis consisted of data drawn from 49 studies of a total of 312,175 patients, a staggering number. The authors included only randomized clinical trials — the most rigorous type of study — and went back all the way to 1966 in their search for relevant trials.
The degree of benefit provided by statin and certain non-statin approaches that work predominantly by increasing the number of receptors in the body to clear out LDL cholesterol was roughly similar. The non-statin approaches included diet, bile acid sequestrants, ezetimibe, and ileal bypass surgery. Additional non-statin drugs assessed included niacin and fibrates. Both types of drugs offered cardiovascular risk reduction as well, though a major caveat regarding the data supporting use of these non-statin drugs was that the trials were not done on top of statins, or did not show clear benefits when added to statins.
Another important observation in this analysis was that lower levels of achieved LDL cholesterol were associated with even lower rates of major coronary events. This held true both for secondary prevention (that is, in patients with known atherosclerosis) as well as for primary prevention (that is, in patients with elevated cholesterol and cardiovascular risk, but without apparent atherosclerosis). The data drawn from the recent studies of the potent injectable PCSK9 inhibitor drugs also seem to support the relationship of lower cholesterol levels being more beneficial. However, it should be noted that large cardiovascular outcome trials are ongoing with these expensive injectable agents, to see if in fact they do decrease heart attack rates to the extent predicted from the large reductions in cholesterol they produce.
Thus, it appears that a variety of methods to lower cholesterol — several drugs and also diet — lower cardiovascular events, such as the chances of developing a heart attack. For patients at high cardiovascular risk, in addition to a healthy diet, statins remain the first-line drug therapy. For patients who cannot tolerate statins, non-statin drugs, including some of the older drugs, may provide a reasonable degree of benefit. The answer to whether even lower degrees of cholesterol reduction achieved by PCSK9 inhibitors further decrease cardiovascular risk is eagerly awaited.
Related Post:
The post Many ways to lower cholesterol will reduce heart disease risk appeared first on Harvard Health Blog.
From: Deepak Bhatt, MD, MPH http://www.health.harvard.edu/blog/many-ways-to-lower-cholesterol-lower-heart-disease-risk-2016100710473
Mayo Clinic Minute: Proton beam therapy bolsters cancer treatment
From: Mayo Clinic http://www.youtube.com/watch?v=vbtyO0WrhmE
China firms happy to sell killer opioid "weapon" to anyone in U.S.
From: http://www.cbsnews.com/news/china-sell-opioid-carfentanil-fentanyl-chemical-weapon-unrestricted-chinese/