03/01/17

Wednesday, March 1, 2017

Bone and joint problems associated with diabetes

From: http://www.mayoclinic.com/diseases-conditions/diabetes/in-depth/diabetes/art-20049314

Germs: Understand and protect against bacteria, viruses and infection

From: http://www.mayoclinic.com/diseases-conditions/infectious-diseases/in-depth/germs/art-20045289

Mom warns about breast-feeding after newborn starves

Doctors say "breast is best," but sometimes it's not enough; "If I had given him just one bottle, he would still be alive," mom says

From: http://www.cbsnews.com/news/moms-warning-goes-viral-after-newborn-dies-from-cluster-feeding/

More evidence tying obesity to certain cancers

Digestive organs may be hardest hit by too much weight, a new study suggests

From: http://www.cbsnews.com/news/more-evidence-tying-obesity-to-certain-cancers/

Does TV Hinder Kindergarten-Readiness?

Lower-income kids harmed more by excess screen time than affluent children, study finds

From: http://www.webmd.com/parenting/news/20170301/does-tv-hinder-kindergarten-readiness?src=RSS_PUBLIC

Wireless Arm Patch May Blunt Migraine Pain

Study found electrical stimulation reduced ache if started soon enough

From: http://www.webmd.com/migraines-headaches/news/20170301/migraine-arm-patch?src=RSS_PUBLIC

Indoor tanning costs U.S. health care millions a year

In a new study, researchers estimate staggering medical costs of skin cancer associated with the use of tanning devices

From: http://www.cbsnews.com/news/indoor-tanning-costs-u-s-healthcare-millions-per-year/

Radiology Nursing – Remy Mella, RN

From: Mayo Clinic http://www.youtube.com/watch?v=mqtPTMItD6c

Radiology Nursing – Ally Villiard, RN

From: Mayo Clinic http://www.youtube.com/watch?v=9RET-3C4BU4

Another Study Ties Obesity to Certain Cancers

Digestive organs may be hardest hit by too much weight, study suggests

From: http://www.webmd.com/cancer/news/20170301/another-study-ties-obesity-to-certain-cancers?src=RSS_PUBLIC

Nerve 'Zap' Treatment May Speed Stroke Recovery

Small study found arm weakness improved when brain was stimulated during physical therapy

From: http://www.webmd.com/stroke/news/20170301/nerve-zap-treatment-may-speed-stroke-recovery?src=RSS_PUBLIC

Antiviral Flu Drugs Safe in Mid-to-Late Pregnancy

No higher rates of complications seen in babies when mom took these meds after 22 weeks of pregnancy

From: http://www.webmd.com/cold-and-flu/news/20170301/antiviral-flu-drugs-safe-in-mid-to-late-pregnancy-study?src=RSS_PUBLIC

Bone and joint problems associated with diabetes

From: http://www.mayoclinic.org/diseases-conditions/diabetes/in-depth/diabetes/art-20049314

Germs: Understand and protect against bacteria, viruses and infection

From: http://www.mayoclinic.org/diseases-conditions/infectious-diseases/in-depth/germs/art-20045289

Facebook improves suicide prevention outreach

Facebook has offered suicide prevention tools for years, but is boosting efforts after teen's recent live-streamed suicide

From: http://www.cbsnews.com/news/facebook-suicide-prevention-outreach-live-video/

Mumps the word: Players hope NHL can contain latest outbreak

In the second outbreak in a little over two years, players are counting on the league being better equipped to contain any spread

From: http://www.cbsnews.com/news/mumps-the-word-players-hope-nhl-can-contain-latest-outbreak/

Chemical Composition, but Not Specific Surface Area, Affects Calcium Retention of Nanostructured Calcium Compounds in Growing Rats [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Low dietary calcium intake and bioavailability may adversely affect bone health. Reducing the size of calcium compounds increases their specific surface area (SSA, expressed as m²/g) and may increase calcium dissolution and bioavailability.

Objective: We investigated the influence of SSA and chemical composition on the bioavailability of calcium and compared in vitro calcium dissolution with in vivo absorption.

Methods: Calcium dissolution was measured in 0.1 M phosphoric acid, whereas color and pH changes of foods were assessed as indicators for potential sensory performance. Calcium absorption, retention, and fractional retention were measured over a 5-d balance study in growing Sprague-Dawley male rats after 21 d of feeding. Femoral and vertebral bone mineral density (BMD) and extensive tissue histology were assessed at study end. The influence of SSA on calcium bioavailability was assessed by comparing the groups fed pure calcium carbonate (CaCO₃) with increasing SSAs of 3, 36, and 64 m²/g (CaCO₃_3, CaCO₃_36 and CaCO₃_64), whereas chemical composition was assessed by comparing the smallest CaCO₃_64, a 50:50 wt:wt percent solution mixture of CaCO₃ and hydroxyapatite_94, and pure hydroxyapatite_100.

Results: In vivo, fractional calcium retention from hydroxyapatite_100 (mean ± SEM: 54.86% ± 0.95%/5 d) was significantly greater than from CaCO₃_64 (49.66% ± 1.15%/5 d) (P = 0.044). Increasing SSA of the pure CaCO₃ did not significantly improve calcium retention. Across all 5 groups, there were no significant differences in BMD or tissue calcification by histology. In vitro calcium dissolution did not correlate with SSA or calcium absorption. In selected food matrixes, hydroxyapatite_100 caused less color change and/or smaller pH increase than did the other calcium compounds.

Conclusions: Our findings suggest that chemical composition rather than SSA is a predictor of nanostructured calcium bioavailability and that in vitro dissolution of nanostructured calcium does not predict in vivo absorption. Although its phosphorus content may limit use in some populations, nanostructured hydroxyapatite may be a promising calcium compound for food fortification.

From: Posavec, L., Hilty, F. M., Baumgartner, J., Buntting, H., Hilbe, M., Kruger, M., Krumeich, F., Grobler, A. F., Zimmermann, M. B. http://jn.nutrition.org/cgi/content/short/147/3/353?rss=1

Riboflavin Deficiency in Rats Decreases de novo Formate Production but Does Not Affect Plasma Formate Concentration [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: The one-carbon metabolism pathway is highly dependent on a number of B vitamins in order to provide one-carbon units for purine and thymidylate biosynthesis as well as homocysteine remethylation. Previous studies have examined folate and vitamin B-12 deficiency and their effects on formate metabolism; as of yet, to our knowledge, no studies on the effects of riboflavin deficiency on formate metabolism have been published.

Objective: Our objective was to determine the effects of riboflavin deficiency on formate metabolism.

Methods: Weanling male rats were randomly assigned either to control, riboflavin-replete (RR) or to experimental, riboflavin-deficient (RD) versions of the AIN-93G diet for 13 d, at which time a constant infusion of [¹³C]-formate was carried out to ascertain the effects of deficiency on formate production. Gas chromatography–mass spectrometry was used to measure plasma formate concentration and [¹³C]-formate enrichment. HPLC, LC–mass spectrometry (MS)/MS, and enzymatic assays were used for the measurement of one-carbon precursors and other metabolites.

Results: RD rats had significantly lower rates of formate production (15%) as well as significantly reduced hepatic methylenetetrahydrofolate reductase activity (69%) and protein concentration (54%) compared with RR rats. There was no difference in plasma formate concentrations between the groups. Plasma serine, a potential one-carbon precursor, was significantly higher in RD rats (467 ± 73 μM) than in RR rats (368 ± 52 μM).

Conclusions: Although deficiencies in folate and vitamin B-12 lead to major changes in plasma formate concentrations, riboflavin deficiency results in no significant difference; this disagrees with the prediction of a published mathematical model. Our observation of a lower rate of formate production is consistent with a role for flavoproteins in this process.

From: MacMillan, L., Lamarre, S. G., daSilva, R. P., Jacobs, R. L., Brosnan, M. E., Brosnan, J. T. http://jn.nutrition.org/cgi/content/short/147/3/346?rss=1

Maize Milling Method Affects Growth and Zinc Status but Not Provitamin A Carotenoid Bioefficacy in Male Mongolian Gerbils [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Vitamin A (VA) and zinc deficiencies are prevalent. Maize is a common staple, and milling affects nutrient and nutrient-modifier profiles.

Objective: We investigated the interaction of maize milling methods (i.e., whole grain compared with refined) in male Mongolian gerbils aged 29–35 d with conventionally bred provitamin A–biofortified (orange) or white maize on VA and zinc status.

Methods: Study 1 (n = 67) was a 2 x 3 milling (whole compared with refined) by VA [no–vitamin A placebo group (VA–), orange, and VA-supplemented group (VA+)] design, with 4 wk of VA depletion followed by six 4-wk treatments (n = 10/treatment). Study 2 (n = 33) was a 2 x 2 milling-by-zinc [no-zinc placebo group (Zn–) compared with zinc-supplemented group (Zn+)] design, including 2 wk of VA depletion followed by four 3-wk treatments (n = 8–9/treatment). For study 1, positive and negative control groups were given supplemental VA at equimolar amounts to β-carotene equivalents consumed by the orange groups (74 ± 5 nmol/d) or placebo, respectively. For study 2, positive and negative control groups were given 152 μg Zn/d or placebo, respectively.

Results: Milling significantly affected zinc concentration, providing 44–45% (whole grain) or 9–14% (refined) NRC requirements. In study 1, orange maize improved liver VA concentrations (mean ± SD: 0.28 ± 0.08 μmol/g) compared with the white maize groups (0.072 ± 0.054 μmol/g). Provitamin A bioefficacy was similar. In study 2, neither zinc nor milling influenced liver retinol. Refined Zn– gerbils weighed less than others by day 14 (46.6 ± 7.1 compared with 56.5 ± 3.5 g, respectively; P < 0.0001). Milling affected pancreas zinc concentrations (refined Zn–: 21.1 ± 1.8 μg Zn/g; whole Zn–: 32.5 ± 5.8 μg Zn/g).

Conclusions: Whole-grain intake improved zinc and did not affect provitamin A bioefficacy. Other factors affected by milling (e.g., shelf life, preference, aflatoxin fractioning) need to be considered to maximize health.

From: Gannon, B. M., Pixley, K. V., Tanumihardjo, S. A. http://jn.nutrition.org/cgi/content/short/147/3/337?rss=1

Digestion-Resistant Dextrin Derivatives Are Moderately Digested in the Small Intestine and Contribute More to Energy Production Than Predicted from Large-Bowel Fermentation in Rats [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: Digestion-resistant dextrin derivatives (DRDDs), including resistant maltodextrin (RM), polydextrose, and resistant glucan (RG), have been developed as low-energy foods. However, data on the resistance of DRDDs to small-intestinal digestion are scarce.

Objective: We sought to determine the site and extent of DRDD breakdown in the rat intestine and to predict its energy contributions.

Methods: In vitro small-intestinal resistance of DRDDs was evaluated by the AOAC method for dietary fiber measurement and by artificial digestion with the use of pancreatic α-amylase and brush-boarder membrane vesicles. In vivo small-intestinal resistance of DRDDs was determined from the feces of male ileorectostomized Sprague-Dawley rats fed a control diet or a diet containing one of the DRDDs at 50 g/kg for 9 d (period 1) and then for 10 d (period 2), during which they received 1 g neomycin/L in their drinking water. Separately, male Sprague-Dawley rats were fed the same diets for 4 wk, and the whole-gut recoveries of DRDDs were determined from feces at days 8–10.

Results: Small-intestinal resistances determined in vitro by artificial digestion (RM: 70%; polydextrose: 67%; RG: 69%) were lower than those measured by the AOAC method (RM: 92%; polydextrose: 80%; RG: 82%). In the ileorectostomized rats, fecal dry-matter excretions were consistently greater in the DRDDs than in the control. The small-intestinal resistances of the DRDDs were 68%, 58%, and 62% in period 1 and 66%, 61%, and 67% during period 2 for RM, polydextrose, and RG, respectively. The resistances did not differ among the DRDDs at either time. In the normal rats, food intakes and body weight gains did not differ among the groups. The whole-gut recovery of RM (13%) was lower than that of polydextrose (33%) and RG (29%), which did not differ.

Conclusions: DRDDs were more digestible in the rat small intestine than the AOAC method. The energy contribution from small-intestine digestibility, not just large-bowel fermentability, must be considered in determining the energy contribution of DRDDs. Whether humans respond similarly needs to be tested.

From: Kondo, T., Handa, K., Genda, T., Hino, S., Hamaguchi, N., Morita, T. http://jn.nutrition.org/cgi/content/short/147/3/330?rss=1

Intake of up to 3 Eggs per Day Is Associated with Changes in HDL Function and Increased Plasma Antioxidants in Healthy, Young Adults [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Background: HDL function may be more important than HDL concentration in determining risk for cardiovascular disease. In addition, HDL is a carrier of carotenoids and antioxidant enzymes, which protect HDL and LDL particles against oxidation.

Objective: The goal of this study was to determine the impact of consuming 0–3 eggs/d on LDL and HDL particle size, HDL function, and plasma antioxidants in a young, healthy population.

Methods: Thirty-eight healthy men and women [age 18–30 y, body mass index (in kg/m²) 18.5–29.9] participated in this 14-wk crossover intervention. Subjects underwent a 2-wk washout (0 eggs/d) followed by sequentially increasing intake of 1, 2, and 3 eggs/d for 4 wk each. After each period, fasting blood was collected for analysis of lipoprotein subfractions, plasma apolipoprotein (apo) concentration, lutein and zeaxanthin concentration, and activities of lecithin-cholesterol acyltransferase, cholesteryl ester transfer protein, and paraoxonase-1.

Results: Compared with intake of 0 eggs/d, consuming 1–3 eggs/d resulted in increased large-LDL (21–37%) and large-HDL (6–13%) particle concentrations, plasma apoAI (9–15%), and lecithin-cholesterol acyltransferase activity (5–15%) (P < 0.05 for all biomarkers). Intake of 2–3 eggs/d also promoted an 11% increase in apoAII (P < 0.05) and a 20–31% increase in plasma lutein and zeaxanthin (P < 0.05), whereas intake of 3 eggs/d resulted in a 9–16% increase in serum paraoxonase-1 activity compared with intake of 1–2 eggs/d (P < 0.05). Egg intake did not affect cholesteryl ester transfer protein activity.

Conclusions: Intake of 1 egg/d was sufficient to increase HDL function and large-LDL particle concentration; however, intake of 2–3 eggs/d supported greater improvements in HDL function as well as increased plasma carotenoids. Overall, intake of ≤3 eggs/d favored a less atherogenic LDL particle profile, improved HDL function, and increased plasma antioxidants in young, healthy adults. This trial was registered at clinicaltrials.gov as NCT02531958.

From: DiMarco, D. M., Norris, G. H., Millar, C. L., Blesso, C. N., Fernandez, M. L. http://jn.nutrition.org/cgi/content/short/147/3/323?rss=1

The Contribution of Intestinal Gluconeogenesis to Glucose Homeostasis Is Low in 2-Day-Old Pigs [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Trump Address: Obamacare, Drug Approvals

President Trump lays out a familiar plan for repealing and replacing the Affordable Care Act, calling for Republicans and Democrats to join forces.

From: http://www.webmd.com/health-insurance/news/20170301/trump-address-obamacare-drug-approvals?src=RSS_PUBLIC

#AsktheMayoMom about Congenital Heart Disease and Pediatric Heart Transplants

From: Mayo Clinic http://www.youtube.com/watch?v=agKITfae-vw

At what age should kids start going to the dentist?

New study explores whether or not preventive dental care helps before age 2

From: http://www.cbsnews.com/news/what-age-should-kids-start-going-to-the-dentist/

Should parents be concerned about MiraLAX use in kids?

Some parents have raised alarming claims about the popular over-the-counter laxative, but the nature of the risk is unclear

From: http://www.cbsnews.com/news/miralax-side-effects-in-kids-should-parents-be-concerned/

10-minute eye surgery could replace reading glasses

Blurry close-up vision – the bane of middle age – has a new treatment option, but it won't turn your eyesight back to a 20-year-old's

From: http://www.cbsnews.com/news/eye-implant-surgery-for-blurry-vision-presbyopia-may-help-some-toss-their-reading-glasses/

What If You Could Take Health Insurance With You?

“Portability” will likely be a buzz word in the health law repeal-and-replace debate, but the concept raises a number of complicated policy issues.

From: http://www.webmd.com/health-insurance/news/20170301/health-insurance-what-if-you-could-take-it-with-you?src=RSS_PUBLIC

Concussions More Likely in Female Athletes

Why remains unclear, researchers say

From: http://www.webmd.com/brain/news/20170228/concussions-more-likely-in-female-athletes?src=RSS_PUBLIC

Study: Bleeding Risk From Common Blood Thinners

Research looked specifically at bleeds inside the skull and near the brain

From: http://www.webmd.com/dvt/news/20170228/study-tracks-bleeding-risk-from-common-blood-thinners?src=RSS_PUBLIC

Mayo Clinic Minute: Tips to prevent cold and flu

From: Mayo Clinic http://www.youtube.com/watch?v=6x2pBKBjJ7k

Weight loss that works: A true story

Many people struggle with being overweight, or even obese. It’s a common topic at office visits. As a doctor, I know that excess weight is associated with potentially serious health conditions — high blood pressure, high blood sugar, high cholesterol — not to mention sleep apnea, fatty liver disease, and back and knee problems, among other things. Patients may also worry about their appearance.

Whether a patient is at risk for medical problems due to being overweight, or if it’s a personal health goal, then it’s my job to provide counseling.

In my experience, most patients consider weight loss drugs or surgery only as a last resort. “I want to lose weight naturally,” they say. Once we screen for (and treat) any contributing medical problems that could be causing weight gain (low thyroid function, polycystic ovarian syndrome, prediabetes, among others), or psychological issues (bulimia, binge-eating disorder, depression, anxiety), I encourage a diet-and-lifestyle approach for many reasons, among them my own personal experience.

A real-life weight loss story

A few years ago, I embarked on a personal weight loss journey. I had had two pregnancies back-to-back, and had gained considerable weight, to the point where my own body mass index was over 30 (obesity range). I was many months postpartum, and realized that the “baby weight” wasn’t going anywhere. As a matter of fact, I had gained even more weight since my daughter was born.

At that point, I had a quandary many people can identify with: I was one of two working parents, with two kids under two. How on earth does one tackle weight loss when one is busy and distracted? What I did was fairly basic, and there is research to back up this approach:¹

Here’s what worked for me:

I resigned myself to the fact that, hey, it took me 18+ months to put on the weight, so it would probably take 18+ months to lose it. As much as I knew about nutrition, I felt like I needed guidance. So I researched a bunch of popular diets and philosophies.
I chose a well-rounded, nutritious diet plan consisting of a wide variety of fruits, vegetables, lean proteins, and healthy fats (and also very low in carbohydrates). It was a popular commercial diet, which I modified to suit my preferences (most of the diets out there are fairly similar). I never bought any of their prepared foods, and used their menu only as a guide, substituting what I liked or had in the pantry where necessary.
I got a small pocket notebook, and started keeping track of everything that I ate. Each page represented a day’s intake, and I counted calories, as best I could. Once a week, I weighed myself, and jotted that down as well.
Exercise in those early days consisted of only a few minutes of sit-ups, pushups, and other in-place calisthenics at nighttime, after the kids had gone to sleep (and before they woke up again overnight).
Yes, I had the occasional slice of cake, glass of wine, chunk of chocolate, piece of baklava (a major downfall), or other treats. I forgave myself those indiscretions, as well as any “vacations” from my dieting, logging, and exercising. I would just pick up where I left off and keep going. And going.
There were stops and starts, and the scale went up and down, but over time, the pounds slowly, slowly came off. As the months went on, I was able to rejoin my gym and add once or twice-weekly workout sessions. As my muscle tone increased, so did my metabolism, and the weight came off faster.
It took over two years, but I lost 50 pounds. In the three years since, I’ve maintained that weight loss within five pounds.

What does the science say about my approach? Let’s take a look.

Diet and weight loss

Studies have shown that just about any diet will result in weight loss, if it’s one that someone can follow.^1,2 Esteemed Yale physician and nutrition expert David Katz examined over 58 popular diets and found that the most successful in terms of both weight loss and nutrition consist of “real food.” By that he means plants, whole grains, nuts and seeds, as well as meat (ideally, from animals that ate plants). Basically, foods closer to nature. The other key is minimizing processed foods, including sugars and flours.³

Without realizing it, I followed Katz’ advice: I ate mostly fruits and vegetables, nuts, seeds, and dairy. I occasionally had whole grains like quinoa or farro, even rice or corn chips. And, of course, an occasional treat. But I had sworn off sugars and flours, for the most part.

Behavior change and weight loss

It’s hard to keep track of how much we eat. But a lot of research shows that when we keep track of intake, we eat less. This is called self-monitoring, and why writing down what I ate and weighed helped me.^4,5,6 There are so many ways to do this nowadays: from the old-school paper-and-pencil method, to apps like MyFitnessFal, or the Weight Watchers points system.⁷

Another key approach: forgive your failures. Studies show that people who “mess up” their diet plan and then “give up” end up gaining, while people who forgive themselves and move on continue to lose. It’s called self-acceptance.^8,9 Look, we’re human. Birthdays, office parties, weddings, random movie nights: they happen, and we celebrate by having the amazing chocolate cake, or Betsy’s famous buffalo chicken dip, waaaay too much champagne, or buttered popcorn. Expect this, enjoy, and then move on.

Exercise and weight loss

Most major weight loss is followed by weight gain, as people revert to their old habits. But, some folks manage to keep it off. How do they do it? Researchers have found that maintaining a healthy diet, ongoing self-monitoring, plenty of self-acceptance, as well as a high level of physical activity are all associated with keeping the pounds off.¹⁰

When I feel like I’m slipping, I start logging again. Nowadays, I use an online fitness app on my phone to more easily keep track of my daily food intake. Red wine and dark chocolate are always in stock in our house, and that’s OK. Exercise is important, too, but in my book, any and all physical activity counts. Two or three workouts a week help me maintain muscle tone and cardiovascular fitness. If I can’t get to the gym, I run. If I can’t run, I do something at home, like five minutes of in-place kickboxing moves, or dancing around the living room like a crazy person with my kids. I take the stairs wherever I am as often as possible. I use a carry basket at the grocery store, and switch from arm to arm while I shop: biceps curls! Hey, it all counts.

Staying at a healthy weight for life

The old adage is “eat less, exercise more,” and this is still true, to some extent. But human beings are psychologically and sociologically complex creatures, and that adage is a lot harder to follow than it sounds. For average adults who do not have contributing medical or psychological issues, a nutritious plant-based diet low in processed foods and carbohydrates, consistent self-monitoring of intake and progress, forgiving oneself when expected lapses occur, all combined with regular physical activity, can result in weight loss for life.

References

Gardner CD, Kiazand A, Alhassan S, et al. Comparison of the Atkins, Zone, Ornish, and LEARN Diets for change in weight and related risk factors among overweight premenopausal women. The A to Z Weight Loss Study: a randomized trial. JAMA, 2005.
Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA, 2005.
Katz and S. Meller. Can We Say What Diet Is Best for Health?Annual Review of Public Health, Vol.35.
Burke LE, Wang J, Sevick MA. Self-monitoring in weight loss: a systematic review of the literature. J Am Diet Assoc., Jan. 2011.
Lim S, O’Reilly S, Behrens H, Skinner T, Ellis I, Dunbar JA. Effective strategies for weight loss in post-partum women: a systematic review and meta-analysis. Obes Rev., Nov. 2015, E-pub Aug 27, 2015.
Hassan Y, Head V, Jacob D, Bachmann MO, Diu S, Ford J. Lifestyle interventions for weight loss in adults with severe obesity: a systematic review. Clin Obes, 2016.
Levine DM, Savarimuthu S, Squires A, Nicholson J, Jay M. Technology-assisted weight loss interventions in primary care: a systematic review. J Gen Intern Med., Jan 2015, E-pub Aug 19 2014.
Rogers JM, Ferrari M, Mosely K, Lang CP, Brennan L. Mindfulness-based interventions for adults who are overweight or obese: a meta-analysis of physical and psychological health outcomes. Obes Rev., Jan. 2017.
Ruffault A, Czernichow S, Hagger MS, Ferrand M, Erichot N, Carette C, Boujut E, Flahault C. The effects of mindfulness training on weight-loss and health-related behaviours in adults with overweight and obesity: A systematic review and meta-analysis. Obes Res Clin Pract., 2016.
Montesi L, El Ghoch M, Brodosi L, Calugi S, Marchesini G, Dalle Grave R. Long-term weight loss maintenance for obesity: a multidisciplinary approach. Diabetes Metab Syndr Obes., Feb. 2016.
Lifestyle: Medicine That Inspires, Huffington Post.

The post Weight loss that works: A true story appeared first on Harvard Health Blog.

From: Monique Tello, MD, MPH http://www.health.harvard.edu/blog/weight-loss-that-works-a-true-story-2017030111218