Wednesday, May 9, 2018

PTSD May Raise Odds for Irregular Heartbeat

It's the first time a connection has been made between post-traumatic stress disorder (PTSD) and "A-fib," which typically arises with age and is the most common type of heart rhythm problem.



From: https://www.webmd.com/heart-disease/atrial-fibrillation/news/20180508/ptsd-may-raise-odds-for-irregular-heartbeat?src=RSS_PUBLIC

FDA declares EpiPen shortage

As many as 400 patients have been unable to fill EpiPen prescriptions since May 2, according to reports

From: http://www.cbsnews.com/news/epipen-shortage-2018-05-09-fda/

African Nation Reports New Ebola Cases

ebola in bloodstream

It's been less than a year since the last incidence of Ebola in the central African country. Eight people were infected and four of them died.



From: https://www.webmd.com/a-to-z-guides/news/20180509/african-nation-reports-new-ebola-cases?src=RSS_PUBLIC

Chondroitin and melanoma: How worried should you be?

Follow me on Twitter @RobShmerling

Chondroitin sulfate is among the most popular supplements in the world. It’s often taken in combination with glucosamine for joint disease — some take it for prevention, others to treat pain.

And yet, evidence that it actually works at all is limited at best. One review of the evidence suggested that of the few studies of chondroitin that were positive, nearly all were funded by makers of the supplement. Despite this, millions of people take it, many of my patients swear by it, and the lack of evidence doesn’t seem to be much of a concern to them. A frequent comment I hear is: “Well, I’m not sure if it’s doing much but it can’t hurt, right?” A new study suggests that maybe it can.

Can chondroitin increase melanoma risk?

Researchers publishing in the medical journal Molecular Cell are raising concerns that chondroitin sulfate may encourage the development or recurrence of melanoma, a potentially deadly form of skin cancer. Here’s what they found:

  • The growth of human melanoma cells with a particular mutation (called V600E) that had been grafted onto the skin of mice was promoted when the mice consumed chondroitin sulfate. About half of human melanomas contain this mutation.
  • Among mice fed chondroitin sulfate, these melanoma tumors were more resistant to an antitumor drug, vemurafenib, than those without the mutation.

Although this research did not actually study people with melanoma, the study authors speculate that for people with precancerous skin growths containing the V600E mutation, taking chondroitin might be a bad idea because it could speed up tumor growth. And if a person had melanoma in the past, taking chondroitin might make recurrence more likely.

The research linking chondroitin and melanoma is preliminary

It’s important to point out that this is preliminary research. Although the tumor cells studied came from humans, a link between chondroitin sulfate use and melanoma in humans has not yet been established. It’s possible that these results aren’t relevant to actual people — for example, the doses or metabolism of chondroitin sulfate may be so different in humans (vs. mice) that these results do not apply to humans. It is not rare that studies in animals do not translate directly to people.

Why does this matter?

Melanoma is not the most common type of skin cancer, but unlike many other skin cancers (such as basal cell cancers), simply removing the cancer doesn’t always cure it. It can spread quickly even years after apparent “cure.” Estimates are that more than 90,000 people learn they have melanoma each year, and more than 9,000 people die of the disease annually.

Here’s my take: this research is quite preliminary, and might turn out to have little relevance to human disease. But if chondroitin sulfate may promote melanoma growth — and it’s not clear that this supplement is particularly helpful anyway — I’d advise against its use, at least until we know more.

The post Chondroitin and melanoma: How worried should you be? appeared first on Harvard Health Blog.



From: Robert H. Shmerling, MD https://www.health.harvard.edu/blog/chondroitin-and-melanoma-how-worried-should-you-be-2018050913792

Babies Like To Hear Other Babies

Researchers found that 5-month-old infants spent 40 percent longer listening to sounds from other infants than to adults making the same sounds.



From: https://www.webmd.com/parenting/baby/news/20180509/babies-like-to-hear-other-babies?src=RSS_PUBLIC

New prostate cancer screening guidelines released

The U.S. Preventive Services Task Force has issued new guidelines for prostate cancer screening. It says men between the ages of 55 and 69 should talk to their doctors about getting the blood test that looks for markers of the disease. The panel had previously advised against routine screening. Dr. David Agus joins "CBS This Morning" from Los Angeles to discuss the guidelines.

From: http://www.cbsnews.com/video/new-prostate-cancer-screening-guidelines-released/

The rising cost of insulin: "Horror stories every day"

As insulin prices surge, a mother recounts the financial squeeze that led to her son's death and that imperils other diabetics

From: http://www.cbsnews.com/news/the-rising-cost-of-insulin-horror-stories-every-day/