As part of the government's commitment to ending the U.S. opioid epidemic, the Food and Drug Administration announced March 22 major label changes for all prescription opioid products, including new boxed warnings about the serious risks of misuse, abuse, addiction, overdose and death.
From: http://www.ada.org/en/publications/ada-news/2016-archive/march/fda-to-require-boxed-warnings-on-opioid-medications
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