Monday, February 15, 2016

Biological modeling of mucus to modulate mucus barriers

A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.



From: Desseyn, J.-L., Gouyer, V., Gottrand, F. http://ajpgi.physiology.org/cgi/content/abstract/310/4/G225?rss=1

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